Increased duration of OTC painkiller use increases risk of hearing loss

Researchers say their findings suggest that a “significant proportion” of hearing loss is owed to paracetamol or NSAID-related ototoxicity. Previous research has linked use of analgesics to an increased risk of hearing loss, but it is unclear if this is affected by duration of painkiller use. To investigate, researchers from the Brigham and Women’s Hospital … Continue reading Increased duration of OTC painkiller use increases risk of hearing loss

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IV, PO, and PR ACETAMINOPHEN/ PARACETAMOL: A QUICK COMPARISON

The 3 formulations available for acetaminophen are intravenous (IV), per oral (PO), and per rectal (PR). Although their pharmacokinetics are all similar, here’s how they differ: IV Acetaminophen:  A generic version of the Ofirmev prescription brand-name formulation isn’t available, making IV acetaminophen significantly more expensive than the PO or PR formulations. The indications for IV … Continue reading IV, PO, and PR ACETAMINOPHEN/ PARACETAMOL: A QUICK COMPARISON